Enzyme Removes HIV from Cells

A study published in the June 29 issue of the magazine Science provides the first evidence that Human Immunodeficiency Virus (HIV) can be fought by removing HIV's DNA from infected cells. A group of German scientists have created a mutant strain of a well-known enzyme that acts as a pair of scissors to "snip out" HIV's DNA sequence that was previously inserted into the larger human cell DNA as part of an HIV infection.

What makes HIV so insidious ... Full Story »

Posted by Dale Penn
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Subjects: Sci/Tech, Health
Topics: Science, HIV/AIDS
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Posted by: Posted by Dale Penn - Jul 2, 2007 - 12:50 PM PDT
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Dale Penn
3.7
by Dale Penn - Oct. 1, 2008

This is good journalism as it sheds light on potentially important scientific progress for treatment of HIV. The article is clear that this is a line of research with much work remaining before we can know if it will present a new treatment option. For those with the disease and their physicians it is always heartening to see that research continues to search for a cure - as opposed to the more prevalent expectation that HIV will become accepted as a treatable disease like diabetes.

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Patricia Blochowiak
5.0
by Patricia Blochowiak - Oct. 1, 2008

This is a clearly presented story about research done at highly-respected institutions and reported in a highly-respected journal. It links the original research, describes the research, gives its limitations, and realistically discusses its implications. Such reputable science reporting is not often found in the general press.

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Carl Pham
5.0
by Carl Pham - Oct. 1, 2008

A nice brief "research note" discussing an interesting attack on HIV infection, namely snipping the integrated DNA out of the host genome. It would have been better had they gone more into the nature of the operational difficulties. We know it's hard to get whole enzymes into the cell (after all, that is tantamount to an invasion), and even harder to get them into the nucleus. How was it done in vitro, in this experiment? Is there any hope for a similar approach in vivo?

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