Nature Podcast: A new way to make Embryonic Stem Cells

... but first, a new way to make ES or Embryonic Stem Cells, but without the need for an embryo, in fact the starting material is a mature skin cell called a fibroblast and two papers in this week's Nature by Rudolf Jaenisch in the US and Shinya Yamanaka in Japan show how switching on four genes called Oct4, Sox2, c-Myc and Klf4 can genetically reprogram specialized adult-type cells and turn them back into Embryonic Stem Cells. Full Story »