All in the Stroma: Cancer's Cosa Nostra

After focusing for decades on what happens within tumor cells to make them go wrong, biologists are turning to the tumor environment and finding a network of coconspirators

Cancer biologists have recently been coming to grips with the fact that tumor cells get a lot of help from the cells around them. Such collusion is not the source of disease: More than 30 years of research have shown that mutations in a cell's own DNA initiate the changes that put it on its destructive path. But "people are realizing that the tumor environment is a coconspirator," says Zena Werb of the University of California, San Francisco (UCSF). ... Full Story »

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Dwight Rousu
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by Dwight Rousu - Oct. 1, 2008

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